Types of Dermal Fillers
The first wrinkle fillers were made from a purified form of collagen which is found naturally in the skin. Although the injection of collagen produced natural-looking results but the collagen began to break down as early as 1 month after treatment. Moreover, they caused allergic reactions in some patients that necessitated allergy tests before the injection. Newer forms of Dermal fillers, however, employ other natural components of the skin that have a longer absorption process and their effect can last up to over a year or two. The most prevalent natural substance used in the fillers is Hyaluronic Acid.
Hyaluronic Acid-Based Fillers
Hyaluronic acid is an essential component of the skin that’s produced by the body naturally. In the human body, it is found in the greatest concentrations in the skin, inside joints, within the eye sockets and in other tissues where it helps retain collagen, increase moisture, and provide elasticity and flexibility. Filler brands such as Juvederm, Prevelle, Restylane are all Hyaluronic Acid based.
Synthetic Wrinkle Fillers
Synthetic Wrinkle Fillers, on the other hand, are made in the lab and do not contain anything found naturally in the skin. Some are a combination of biodegradable substances that stimulate the production of collagen. The longer-lasting synthetic fillers contain products such as polymethyl methacrylate (PMMA) microspheres that remain under the skin for the continuous support of skin for up to 5 years. These fillers have longer lasting results however they are more likely to cause adverse side effects and if not administered correctly may result in disfiguration. Brand names in synthetic fillers include Bellafill, Radiesse, Sculptra.
Silicone fillers are not approved to be used as a facial wrinkle treatment and have fallen out of favor by plastic surgeons since as a dermal filler, silicone is unpredictable, its removal after use is difficult, and that the risk of complications is too serious.